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USP30 inhibitor 11
CAS No. 2067332-64-1
USP30 inhibitor 11( —— )
Catalog No. M33160 CAS No. 2067332-64-1
USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 μΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 327 | Get Quote |
|
| 5MG | 511 | Get Quote |
|
| 10MG | 753 | Get Quote |
|
| 25MG | 1086 | Get Quote |
|
| 50MG | 1500 | Get Quote |
|
| 100MG | 1971 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameUSP30 inhibitor 11
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NoteResearch use only, not for human use.
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Brief DescriptionUSP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 μΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.
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DescriptionUSP30 inhibitor 11 is a selective and potent ubiquitin specific peptidase 30 (USP30) inhibitor with an IC50 of 0.01 μΜ, the example 83 extracted from patent WO2017009650A1. USP30 inhibitor 11 is used for the study of cancer and conditions involving mitochondrial dysfunction.
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In VitroUSP30 is a 517 amino acid protein which is found in the mitochondrial outer membrane. It is the sole deubiquitylating enzyme bearing a mitochondrial addressing signal and has been shown to deubiquitylate a number of mitochondrial proteins.USP30 inhibitor 11 (0.01-30 μΜ; λEx=540 nm; λEm=590 nm) inhibits USP30 biochemical activity with an IC50 of 0.01 μΜ in a USP30 biochemical IC50 assay.
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorDUB
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Research Area——
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Indication——
Chemical Information
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CAS Number2067332-64-1
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Formula Weight368.41
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Molecular FormulaC17H16N6O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (90.47 mM; Ultrasonic )
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SMILESCOc1ccc(nc1C#N)-c1csc(n1)N(C)C(=O)[C@@H]1CCCN1C#N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mark Kemp, et al. Cyanopyrrolidines as dub inhibitors for the treatment of cancer. Patent WO 2017009650 A1.
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USP30 inhibitor 11
USP30 inhibitor 11 (USP30-IN-11) is a selective USP30 inhibitor (IC50: 0.01 μΜ) that inhibits SVA and can be used in studies of cancer, mitochondrial dysfunction and Parkinson's.
